Research Focus

Plant adaptation is an evolutionary process that increases survival and reproduction in  newly encountered climatic conditions. Understanding the molecular mechanistic knowledge of adaptation to environmental stress has important implications in evolutionary ecology. The adaptation process underlies transcriptional, translational, metabolic and epigenetic control during the developmental process. Research in our lab focusing on comprehensive mapping of transcriptome, proteome, metabolome and epigenome of medicinal plants that will be helpful for understanding the multilayered control of adaptation process.  

Achievements / Awards

SERB Early Carrier research Award 2018

Assistant Professor of Academy of Scientific and Innovative Research (AcSIR) (2016)

Awarded D.S Kothari Postdoctoral Fellowship (2014-2017) and DBT-RA (2014-2019; Not availed).

Received DBT-JRF (2008-2013) and DBT fellowship (2006-2008) during M.Sc.

Qualified NET-LS(2008), GATE(Percentile: 98.93%; Dec. 2007) and JNU CEEB (2006).

Editorial/Reviewer roles:-

Review Editor, Frontiers in Molecular Biosciences, Frontiers in Plant Genomics, and Frontiers in Molecular Diagnostics and Therapeutics

Reviewer of National and International Journals like Journal of Proteomics, Scientific report, Plant physiology and Biochemistry, Journal of Biosciences, Journal of Protein and Proteomics

Major Publications

Identification and quantification of eight alkaloids in Aconitum heterophyllum using UHPLC-DAD-QTOF-IMS: A valuable tool for quality control, Ashwani Punia, Robin Joshi^* Rajiv Kumar^*, Phytochemical Analysis.2022;1–14, DOI:10.1002/pca.3164. IF 3.02

Nutritional quality evaluation and proteome profile of forage species of Western Himalaya, Rajiv Kumar^*,Robin Joshi, Raman Kumar, Vidyashankar Srivatsan, Satyakam, Amit Chawla, Vikram Patial, Sanjay Kumar, Grassland Science, 2021, DOI: 10.1111/grs.12357. IF 1.6

Protein-Cloaked Nanoparticles for Enhanced Cellular Association and Controlled Pathophysiology via Immunosurveillance Escape, Aqib Iqbal Dar, Syed M. S. Abidi, Shiwani Randhawa, Robin Joshi, Rajiv Kumar, and Amitabha Acharya*, ACS Appl. Mater. Interfaces 2021, https://doi.org/10.1021/acsami.1c20719. IF 9.2

In-depth assembly of organ and development dissected Picrorhiza kurroa proteome map using mass spectrometry, Manglesh Kumari, Upendra Kumar Pradhan, Robin Joshi, Ashwani Punia, Ravi Shankar & Rajiv Kumar*, BMC Plant Biology 21: 604, 2021, https://doi.org/10.1186/s12870-021-03394-8. IF 4.21

Evaluating Peptides of Picrorhiza kurroa and Their Inhibitory Potential against ACE, DPP-IV, and Oxidative Stress. Shweta Thakur, Jyoti Chhimwal, Robin Joshi, Manglesh Kumari, Yogendra Padwad*, and Rajiv Kumar* Journal of Proteome Research, 2021, https://doi.org/10.1021/acs.jproteome.1c00081. IF 4.46

Insights from proteomics in kidney disease diagnosis and various in vitro and in vivo experimental models.Vikram Patial*, Garima Dadhich, Rajiv Kumar*. Animal Biotechnology for Livestock Production Vol.2 2021 (Accepted).

Systemic acquired resistance specific proteome of Arabidopsis thaliana. Rajiv Kumar, Pragya Barua, Niranjana Chakraborty & Ashis Kumar Nandi. Plant cell report. 2020, doi: 10.1007/s00299-020-02583-3. IF 4.57

Metabolic signatures provide novel insights to Picrorhiza kurroa adaptation along the altitude in Himalayan region. Manglesh Kumari, Robin Joshi & Rajiv Kumar*. Metabolomics. 2020; 16:77, doi: 10.1007/s11306-020-01698-8. IF 4.20

Elevated CO2 and temperature influence key proteins and metabolites associated with photosynthesis, antioxidant and carbon metabolism in Picrorhiza kurroa. Rajiv Kumar*, Robin Joshi, Manglesh Kumari, Reema Thakur, Dinesh Kumar*, Sanjay Kumar*. Journal of proteomics. 2020; 219:103755, doi: 10.1016/j.jprot.2020.103755. IF 4.04

Unveiling Taenia solium kinome profile and its potential for new therapeutic targets. Naina Arora, Anand Raj, Farhan Anjum, Rimanpreet kaur, Suraj Singh Rawat, Rajiv Kumar, Shweta Triphati, Gagandeep Singh & Amit Prasad. Expert review of proteomics. 2020; 17:85-91, doi: 10.1080/14789450.2020.1719835. IF 3.94

Regulation of color transition in purple tea (Camellia sinensis). Manglesh Kumari, Shweta Thakur, Ajay Kumar, Robin Joshi, Prakash Kumar, Ravi Shankar, Rajiv Kumar*. Planta. 2020; 251:35, doi: 10.1007/s00425-019-03328-7. IF 4.11

Neglected Agent Eminent Disease: Linking Human Helminthic Infection, Inflammation, and Malignancy. Naina Arora, Rimanpreet Kaur, Farhan Anjum, Shweta Tripathi, Amit Mishra, Rajiv Kumar and Amit Prasad. Front. Cell. Infect. Microbiol. 2019, https://doi.org/10.3389/fcimb.2019.00402. IF 4.83

Usnic acid modifies MRSA drug resistance through down-regulation of proteins involved in peptidoglycan and fatty acid biosynthesis. Sneha Sinha, Vivek Kumar Gupta, Parmanand Kumar1, Rajiv Kumar, Robin Joshi, Anirban Pal and Mahendra P. Darokar FEBS Open Bio. 2019; 9:2025–2040, doi: 10.1002/2211-5463.12650. IF 2.69

Adaptive mechanisms of medicinal plants along altitude gradient: contribution of proteomics. Kumar, R*. & Kumari, M. Biologia Plantarum 2018; 62(4):630-640, DOI: 10.1007/s10535-018-0817-0. IF 1.74

Nuclear phosphoproteome of developing chickpea (Cicer arietinum L.) and Protein-Kinase interaction network. Kumar R, Kumar A, Subba P, Gayali S, Barua P, Chakraborty S, Chakraborty N. J Proteomics. 2014 13; 105:58-73, doi: 10.1016/j.jprot.2014.04.002. IF 4.04

Comparative proteomics of dehydration response in the rice nucleus: new insights into the molecular basis of genotype-specific adaptation. Jaiswal DK, Ray D, Choudhary MK, Subba P, Kumar A, Verma J, Kumar R, Datta A, Chakraborty S, Chakraborty N. Proteomics. 2013;13(23-24):3478-97, doi: 10.1002/pmic.201300284. IF 4.0

Characterization of the nuclear proteome of a dehydration-sensitive cultivar of chickpea and comparative proteomic analysis with a tolerant cultivar. Subba P, Kumar R, Gayali S, Shekhar S, Parveen S, Pandey A, Datta A, Chakraborty S, Chakraborty N. Proteomics. 2013,12-13,1973-92, doi: 10.1002/pmic.201200380. IF 4.0

Phosphoproteomic Dynamics of Chickpea (Cicer arietinum L.) Reveals Shared and Distinct Components of Dehydration Response. Subba P, Barua P, Kumar R, Datta A, Soni KK, Chakraborty S, Chakraborty N. J Proteome Res. 2013;12(11):5025-47, doi: 10.1021/pr400628j. IF 4.46

Analysis of the grass pea proteome and identification of stress-responsive proteins upon exposure to high salinity, low temperature, and abscisic acid treatment. Chattopadhyay A, Subba P, Pandey A, Bhushan D, Kumar R, Datta A, Chakraborty S, Chakraborty N. Photochemistry. 2011,72,1293-307, doi: 10.1016/j.phytochem.2011.01.024. IF 4.07

Citation: http://scholar.google.co.in/citations?user=wmI_PAYAAAAJ&hl=en

Patents

N.A.

Research Group

Lab members

Miss Manglesh kumari (UGC JRF) 

Miss Shweta Thakur (SRF)

Mr. Satyakam (UGC JRF)

Mr. Ashwani (CSIR JRF)

Mr. Vishal Saini (CSIR JRF)

Miss Monika Chouhan (CSIR JRF)

Dr. Robin Joshi (STO)

Mr. Sonu (Lab attendent)