Dr. Upendra Sharma
Research Focus
Group Website: C-H Activation & Phytochemistry
Organic Synthesis & Catalysis
C-H Activation/functionalization
Heterocycles Synthesis
Phytochemistry (Himalayan Medicinal Plants)
Isolation and structure elucidation of plant secondary metabolites
Standardization of plant extracts (targetted activity & four marker compounds)
Development of analytical methods (UPLC, GC, and NMR)
Chemical profiling using NMR (1D & 2D), UPLC-MS/MS, and GC-MS/MS
Medicinal Chemistry
Discovery of new heterocycles as potential therapeutic agents
Scientific validation of plant traditional knowledge (Ayush or Phytopharma route)
Funding
Project Completed:10 (PI: 05; Co-PI: 05)
ProjectOngoing:10 (PI: 02; Co-PI: 08)
Selected Publications in the last three years
Organic Synthesis and Catalysis
139. The Journal of Organic Chemistry, 2022, doi.org/10.1021/acs.joc.2c00752. [LInk]
138. Catalysis Review, 2022, doi.org/10.1080/01614940.2022.2097640.
137. Advanced Synthesis & Catalysis, 2022, 364, 897. [Link]
136. Asian Journal of Organic Chemistry, 2022, 11, e202100804. [Link]
135. The Chemical Records, 2022, 22, e202100271. [Link]
134. Chemical Communications, 2021, 57, 11613. [LInk] [Highlighted on Front Cover] [Link]
133. Organic & Biomolecular Chemistry, 2021, 19, 9675. [Link]
132. The Journal of Organic Chemistry, 2021, 86, 13754 . [Link]
131. European Journal of Organic Chemistry, 2021, 2021, 5443. [Link]
130. React. Chem. Eng., 2021, 6, 2087.[Link] [Invited forEmerging Investigators Series]
129.The Journal of Organic Chemistry, 2022,86, 6612 [Link]
128.The Journal of Organic Chemistry,2021, 86, 6449. [Link]
127.Organic & Biomolecular Chemistry, 2021, 19, 4014. [Link]
126.Catalysis Reviews,2020, doi.org/10.1080/01614940.2020.183.9849. [Link]
125.ACS Sustainable Chemistry & Engineering, 2020, 8, 12902. [Link]
124. Chemistry-A European Journal, 2020, 26, 4396 [Hot Paper]. [Link]
123.Organic Letters, 2020, 22, 305. [Link]
122. The Journal of Organic Chemistry, 2020, 85, 11844 [Most Read Article]. [Link]
121. The Journal of Organic Chemistry, 2020, 85, 9244. [Link]
120. The Journal of Organic Chemistry, 2020, 85, 1181. [Link]
Phytochemistry
119. Sepration and Purification Technology, 2022, 294, 121105. [Link]
118. Frontiers in Endocrinology, 2022, accepted.
117. Journal of Ethanopharmacology, 2022, 287, 114931. [Link]
116. Natural Product Research, 2022, 36, 37. [Link]
115. Molecules, 2022, 27, 3478. [LInk]
114. Molecules, 2022, 27, 633. [Link]
113. BMC Complementary Medicine and Therpies, 2022, 22, 114. [Link]
112. J. Biomol. Struct. Dyn., 2021, doi.org/10.1080/07391102.2021.2003864. [Link]
111. Scientific Reports, 2021, 20095. [Link]
110. Journal of Ethnopharmacology, 2021, 274, 113850. [Link]
109. Analytical Science Advance, 2021, 2, 579-593. [Link]
108. Journal of Pharmacy and Pharmacology, 2021, 73, 487. [Link]
107. Pest Management Science, 2021, 77, 956. [Link]
106. Journal of Molecular Graphics and Modelling, 2021, 106, 107916.
105. Journal of Ethnopharmacology, 2020, 262, 113185. [Link]
104. Phytochemical Analysis, 2020, 31, 861. [Link]
103. Natural Product Research, 2020, 34, 233. [Link]
102. Natural Product Research, 2020, 34, 2051. [Link]
Complete List of Publications
Achievements / Awards
Member of Early Career Board of Science of Synthesis (2022-). [Link]
One Year Advance Promotion i.e. Merit Promotion from Scientist to Senior Scientist.
Member of Early Career Advisory Board of Asian Journal of Organic Chemistry. [Link]
Manjushree Pal Memorial Award for Best Oral Presentation from Ethanopharmacology Society of India, Kolkata (2017)
Thieme Chemistry Journal Award (2016)
Postdoc Fellowship KAIST, South Korea (2014)
D S Kothari Postdoc Fellowship (2012)
Fast Track Young Scientist project for three years (2012)
CSIR Senior Research Fellowship (2009)
CSIR-Junior Research Fellowship (2007)
GATE (2007)
CSIR-NET (2006)
Major Publications
Book Chapters
9. Quinolines (Update 2022)
U. Sharma,* R. Kumar, S. S. Gupta, D. Chandra.
Science of Synthesis Knowledge Updates (Thieme), 2022, 2, 63-327. [Link]
8. Integrated Approach for the Quality Assurance of Commercially Important Himalayan Medicinal Plants.
P. S. Bora, P. S. Suresh, S. Kumari, Anmol, S. Puri, and U. Sharma.*
Ekiert H. M., Ramawat K. G., Arora J. (eds)
Medicinal Plants. Sustainable Development and Biodiversity (Springer), 2021, 28, 721-768. [Link]
7. Steroidal Sapogenins from Genus Trillium: Chemistry, Synthesis, and Opportunities in Neuro-active Steroids Designing.
P. S. Suresh, V. Bhatt, P. P. Singh, and U. Sharma.*
Studies in Natural Product Chemistry (Elsevier), 2021, 68, 67-95 . [Link]
6. Direct Arylation via C-H activation.
U. Sharma, A. Modak, S. Maity, A. Maji, and D. Maiti.*
Thomas CoIacot eds., Introduction to New Trends in Cross-Coupling: Theory and
Applications (RSC), 2014. [Link]
- List of Book Chapters
Patents
3. An Eco-friendly Process for Isolation of Fiber from Plant Species and Product thereof.
M. Sharma, S. Thakur, U. Sharma, and S. Kumar.
Ref. No. 202011034404. Date of Filing: 11-08-2020.
2. Palladium-Catalyzed Synthesis of Benzofurans and Coumarins from Phenols and Olefins.
D. Maiti, U. Sharma, and N. Tagoti.
Indian Patent No. 299110; Date of Grant: 24-07-2018.
1. Benzothiazole Substituted Phthalimide Analogues as Potential Angiogenesis Inhibitors.
B. Singh, S. Chattergi, N. Kumar and U. Sharma.
Indian Patent No. 318680; Date of Grant: 22-08-2019.
Research Group
Postdoc Fellow
Dr. Patil Shivprasad Suresh
Dr. Ankit Kumar Dhiman
Ph.D. Fellows
Mr. Devesh Chandra
Ms. Diksha Parmar
Ms. Surekha Kumari
Mr. Sumit
Ms. Manisha
Mr. Anmol
Mr. Rohit Kumar
Mr. Shiv Shankar Gupta
Mr. Prithvi Pal Singh
Project Fellow
Mr. Gaurav Aggarwal
Mr. Sarthi
Ms. Tamanna Sharma
Group Alumni
Ph.D. Thesis Awarded
Dr. Patil Shivprasad Suresh, Feb. 2022.
Dr. Ankit Kumar Dhiman, December 2021.
Dr. Inder Kumar, July 2021, Current Position: Asst. Prof. at Govt. Degree College (HPU)
Dr. Rakesh Kumar, Feb. 2020; Current Position: Postdoc Fellow [Stepien's Group]
Dr. Ritika Sharma, July 2019
Dr. Deepali Katoch, July 2019
Dr. Vinod Bhatt, Feb. 2018
Project Fellows
Ms. Divya Rana, PA-II, Feb. 2018-June 2019.
Ms. Shivani Puri, PA-II, Sept. 2018-March 2020.
Ms. Kavita Devi, PA-II, July 2019-March 2020.
Postdocs
Dr. Vinod Bhatt, Postdoc, 2018-2019.
Dr. Ashun Chaudhary, Postdoc, 2016-2018; Current Position: Asst. Prof. at CUHP.
Dr. Rakesh Kumar, Postdoc, 2016-2017; Current Position: Asst. Prof. at NIT Jalandhar.
Prospective Team Members
Two Ph.D. Positions Available in the Area of C-H Activation for JRF Candidates.
Postdoc Positions are Available for Self-Motivated Persons.