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Dr. Upendra Sharma

Designation
Senior Scientist
Specialisation
Catalysis C-H Activation Natural Product Chemistry Analytical Chemistry
Qualification
Ph.D.
Email
upendra@ihbt.res.in
Phone
01894-233339 Ext. 449

Research Focus

Group WebsiteC-H Activation & Phytochemistry 

 

Organic Synthesis & Catalysis

C-H Activation/functionalization

    Heterocycles Synthesis 

Phytochemistry (Himalayan Medicinal Plants)

Isolation and structure elucidation of plant secondary metabolites

    Standardization of plant extracts (targetted activity & four marker compounds) 

Development of analytical methods (UPLC, GC, and NMR) 

   Chemical profiling using NMR (1D & 2D), UPLC-MS/MS, and GC-MS/MS

Medicinal Chemistry 

Discovery of new heterocycles as potential therapeutic agents 

    Scientific validation of plant traditional knowledge (Ayush or Phytopharma route)

 

Funding 

      Project Completed:10 (PI: 05; Co-PI: 05)

      ProjectOngoing:10 (PI: 02; Co-PI: 08)

 

 

Selected Publications in the last three years

 

Organic Synthesis and Catalysis

139. The Journal of Organic Chemistry,  2022, doi.org/10.1021/acs.joc.2c00752. [LInk]

138. Catalysis Review, 2022, doi.org/10.1080/01614940.2022.2097640. 

137. Advanced Synthesis & Catalysis, 2022, 364, 897. [Link]

136. Asian Journal of Organic Chemistry, 202211, e202100804. [Link]

135. The Chemical Records, 2022, 22, e202100271.  [Link]

134. Chemical Communications, 202157, 11613. [LInk] [Highlighted on Front Cover] [Link]

133. Organic & Biomolecular Chemistry, 2021, 19, 9675. [Link]

132. The Journal of Organic Chemistry,  2021, 86, 13754 . [Link]

131. European Journal of Organic Chemistry20212021, 5443. [Link]

130. React. Chem. Eng., 2021, 6, 2087.[Link] [Invited forEmerging Investigators Series]

129.The Journal of Organic Chemistry, 2022,86, 6612 [Link]

128.The Journal of Organic Chemistry,2021, 86, 6449. [Link]

127.Organic & Biomolecular Chemistry, 2021, 19, 4014. [Link]

126.Catalysis Reviews,2020, doi.org/10.1080/01614940.2020.183.9849. [Link]

125.ACS Sustainable Chemistry & Engineering2020, 8, 12902. [Link]  

124. Chemistry-A European Journal2020, 26, 4396 [Hot Paper]. [Link]

123.Organic  Letters,  2020, 22, 305. [Link]

122. The Journal of Organic Chemistry202085, 11844 [Most Read Article]. [Link]

121. The Journal of Organic Chemistry202085, 9244. [Link]

120. The Journal of Organic Chemistry, 2020, 85, 1181. [Link]

 

Phytochemistry 

119. Sepration and Purification Technology, 2022294, 121105. [Link]

118. Frontiers in Endocrinology, 2022, accepted.

117. Journal of Ethanopharmacology,  2022,  287, 114931. [Link] 

116. Natural Product Research, 2022, 36, 37. [Link

115. Molecules, 2022, 27, 3478. [LInk]

114. Molecules,  2022, 27, 633. [Link]

113. BMC Complementary Medicine and Therpies,  202222, 114. [Link]

112. J. Biomol. Struct. Dyn., 2021doi.org/10.1080/07391102.2021.2003864. [Link]

111. Scientific Reports, 202120095. [Link]

110Journal of Ethnopharmacology,  2021, 274, 113850. [Link]

109. Analytical Science Advance, 2021, 2, 579-593. [Link]

108Journal of Pharmacy and Pharmacology, 2021, 73, 487. [Link]

107. Pest Management Science, 2021, 77, 956. [Link]

106Journal of Molecular Graphics and Modelling, 2021, 106, 107916.

105. Journal of Ethnopharmacology, 2020, 262, 113185. [Link]

104. Phytochemical Analysis, 2020, 31, 861. [Link]

103. Natural Product Research, 2020, 34, 233. [Link]

102. Natural Product Research, 202034, 2051. [Link]

 

 

 Complete List of  Publications

Achievements / Awards

Member of Early Career Board of Science of Synthesis (2022-). [Link]

One Year Advance Promotion i.e. Merit Promotion from Scientist to Senior Scientist.

Member of Early Career Advisory Board of Asian Journal of Organic Chemistry. [Link]

Manjushree Pal Memorial Award for Best Oral Presentation from Ethanopharmacology Society of India, Kolkata (2017)

Thieme Chemistry Journal Award (2016)

Postdoc Fellowship KAIST, South Korea (2014)

D S Kothari Postdoc Fellowship (2012)

Fast Track Young Scientist project for three years (2012)

CSIR Senior Research Fellowship (2009)

CSIR-Junior Research Fellowship (2007)

GATE (2007)

CSIR-NET (2006) 

Major Publications

Book Chapters

9. Quinolines (Update 2022)

U. Sharma,* R. Kumar, S. S. Gupta, D. Chandra.

Science of Synthesis Knowledge Updates (Thieme), 2022, 2, 63-327. [Link]

 

8. Integrated Approach for the Quality Assurance of Commercially Important Himalayan Medicinal Plants.

 P. S. Bora, P. S. Suresh, S. Kumari, Anmol, S. Puri, and U. Sharma.* 

Ekiert H. M., Ramawat K. G., Arora J. (eds)  

Medicinal Plants. Sustainable Development and Biodiversity (Springer), 2021, 28, 721-768[Link]

 

7. Steroidal Sapogenins from Genus Trillium: Chemistry, Synthesis, and Opportunities in Neuro-active Steroids Designing. 

P. S. Suresh, V. Bhatt, P. P. Singh, and U. Sharma.*

Studies in Natural Product Chemistry (Elsevier), 2021, 68, 67-95 . [Link

 

6. Direct Arylation via C-H activation.

U. Sharma, A. Modak, S. Maity, A. Maji, and D. Maiti.*

Thomas CoIacot eds., Introduction to New Trends in Cross-Coupling: Theory and   

Applications (RSC), 2014. [Link]

 

  1. List of Book Chapters

Patents

3. An Eco-friendly Process for Isolation of Fiber from Plant Species and Product thereof. 

M. Sharma, S. Thakur, U. Sharma, and S. Kumar. 

Ref. No. 202011034404. Date of Filing: 11-08-2020.  

 

2. Palladium-Catalyzed Synthesis of Benzofurans and Coumarins from Phenols and Olefins.

D. Maiti, U. Sharma, and N. Tagoti.  

Indian Patent No. 299110; Date of Grant: 24-07-2018.

 

1. Benzothiazole Substituted Phthalimide Analogues as Potential Angiogenesis Inhibitors.

B. Singh, S. Chattergi, N. Kumar and U. Sharma.  

Indian Patent No. 318680; Date of Grant: 22-08-2019.

  1.  

Research Group

Postdoc Fellow

Dr. Patil Shivprasad Suresh

Dr. Ankit Kumar Dhiman

 

Ph.D. Fellows

Mr. Devesh Chandra

Ms. Diksha Parmar

Ms. Surekha Kumari

Mr. Sumit

Ms. Manisha

Mr. Anmol

Mr. Rohit Kumar

Mr. Shiv Shankar Gupta

Mr. Prithvi Pal Singh

 

Project Fellow

Mr. Gaurav Aggarwal

Mr. Sarthi

Ms. Tamanna Sharma

 

Group Alumni  

 

Ph.D. Thesis Awarded

Dr. Patil Shivprasad Suresh, Feb. 2022.

Dr. Ankit Kumar Dhiman, December 2021.

Dr. Inder Kumar, July 2021, Current Position: Asst. Prof. at Govt. Degree College (HPU) 

Dr. Rakesh Kumar, Feb. 2020; Current Position: Postdoc Fellow [Stepien's Group]

Dr. Ritika Sharma, July 2019

Dr. Deepali Katoch, July 2019 

Dr. Vinod Bhatt, Feb. 2018

 

Project Fellows

Ms. Divya Rana, PA-II, Feb. 2018-June 2019.

Ms. Shivani PuriPA-II, Sept. 2018-March 2020. 

Ms. Kavita Devi, PA-II, July 2019-March 2020.

 

Postdocs

Dr. Vinod Bhatt, Postdoc, 2018-2019.

Dr. Ashun Chaudhary, Postdoc, 2016-2018; Current Position: Asst. Prof. at CUHP.

Dr. Rakesh Kumar, Postdoc, 2016-2017; Current Position: Asst. Prof. at NIT Jalandhar.

 

Prospective Team Members 


Two Ph.D. Positions Available in the Area of C-H Activation for JRF Candidates.

Postdoc Positions are Available for Self-Motivated Persons.