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Dr. Pralay Das

Designation
Senior Principal Scientist
Specialisation
Organic Chemistry
Qualification
Ph.D.
Email
pdas@ihbt.res.in
Phone
01894-233339 Ext. 431

Research Focus

  • Development of polystyrene supported nanocomposite materials as catalyst (Pd@PS, Rh@PS, Au@PS, Ru@PS, etc.) for C-C, C-X coupling, oxidation, carbonylation, oxidative esterification and reduction reactions emphasis on regio- and chemo-selectivity.
  • Heterogeneous nano-catalytic approaches for CO/CO2 fixation reactions using oxalic acid as bench stable C1 surrogate.
  • Semi-synthetic approaches for total synthesis of biologically active benzosuberene/ benzocycloheptene compounds from Cedrus deodara oil, a natural precursor.
  • Scalable process for commercially important cyclohexane-1,3-diones production.
  • Furan based bio-chemicals production from bio-mass, scale-up process.

Achievements / Awards

1 2002-2004 Junior Research Fellowship during Ph.D.
2 2004-2005 Senior Research Fellowship during Ph.D.
3 2005-2007 Post-Doctoral Fellowship, Umea University, Umea, Sweden.
4 2003-Continuing Continuing: Life Member- Chemical Research Society of India, Member ID: LM551.
5 2006: Tetrahedron Letters Most Cited Paper 2003–06 Award” by Elsevier Ltd. Oxford, UK. Microwave-assisted Suzuki coupling on a KF–alumina surface: synthesis of polyaryls, Basudeb Basu, Pralay Das, Md. M. H. Bhuiyan and Satadru Jha, Tetrahedron Letters, 2003, 44(19), 3817-3820.
6 2011-12 Member of American Nano Society, Member ID: 113120.
7 2016 ACS Publications Award, Certificate of Recognition for Reviewing Activities.
8 2019-2021 Bentham Ambassador, Bentham Science Publishers.
9 2020 Honorary Rosalind (Franklin) Member of London Journals Press, #UB66344.
10 2021-2022 Affiliate member of Royal Society of Chemistry (RSC).

 

Major Publications

93. Arvind Singh Chauhan, Ajay Kumar, Ajay Kumar Sharma, Dr. Pralay Das. Pd-Catalysed Decarbonylation Free Approach to Carbonylative Esterification of 5-HMF to Its Aryl Esters Synthesis Using Aryl Halides and Oxalic Acid as C1 Source, Chemistry – A European Journal, 2021, https://doi.org/10.1002/chem.202101827 (IF-5.236)

92. Shaifali, Sheetal, Dr. Pralay Das. Supported Palladium Catalyzed Carbonylative Coupling Reactions using Carbon Monoxide as C1 Source. The Chemical Record, 2021, https://doi.org/10.1002/tcr.202100157 (IF- 6.771)

91. Dharminder Sharma, Manish Kumar, Pralay Das. Synthetic approaches for cyclohexane-1,3-diones: A versatile precursor for bioactive molecules. Synthetic Communications, 2021, https://doi.org/10.1080/00397911.2021.1946824 (IF-1.79)

90. Jatin Sharma, Vijay Kumar Bhardwaj, Pralay Das, Rituraj Purohit, Plant-based analogues identified as potential inhibitor against tobacco mosaic virus: A biosimulation approach. Pesticide Biochemistry and Physiology, 2021, Volume 175, June 2021, 104858(IF-3.963)

89. Rahul Singh, Vijay Kumar Bhardwaj, Pralay Das, Rituraj Purohit, A computational approach for rational discovery of inhibitors for non-structural protein 1 of SARS-CoV-2. Computers in Biology and Medicine, 2021, Volume 135, August 2021, 104555 (IF- 4.589)

88. Ajay Kumar, Arvind Singh Chauhan, Pralay Das*. Lignocellulosic biomass and carbohydrates as feed-stock for scalable production of 5-hydroxymethylfurfural, Cellulose 2021, 28, 3967-3980. (IF-5.04)

87. Richa Bharti, VK Bhardwaj, C Bal Reddy, Rituraj Purohit, Pralay Das*. Benzosuberene-sulfone analogues synthesis from Cedrus deodara oil and their therapeutic evaluation by computational analysis to treat type 2 diabetes, Bioorganic Chemistry 2021, 112, 104860. (IF-5.27)

86. Arvind Singh Chauhan, Ajay Kumar, Pralay Das*. Metal Catalyst and Hydrogen Gas-Free Selective Reduction of Biomass-Derived Substituted Furfuraldehyde to Alkyl Furan as a Key Biofuel Additive, Org. Process Res. Dev. 2021, 25, 4, 892-899. (IF-3.3)

85. Yamini, Saurabh Sharma, Pralay Das*. Rhodium catalyzed 2‐alkyl‐benzimidazoles synthesis from benzene‐1,2‐diamines and tertiary alkylamines as alkylating agents, Applied Organometallic Chemistry 2021,doi.org/10.1002/aoc.6278. (IF-4.10)

84. Shaifali, Pushkar Mehara, Ashish Kumar, Pralay Das*.Pd/C catalyzed cascade synthesis of 2‐arylquinazolinones from 2‐iodoacetanilides employing ammonia and CO precursors, ChemCatChem, 2021, doi.org/10.1002/cctc.202100152.  (IF- 5.68)

83. Dhananjay Bhattacherjee, Matiur Rahman, Sumit Ghosh, Avik Bagdi, Grigory Zyryanov, Oleg Chupakhin, Pralay Das*, Alakananda Hajra. Advances in Transition‐Metal Catalyzed Carbonylative Suzuki‐Miyaura Coupling Reaction: An Update, Adv. Synth. Catal. 2021, 363, 1597-1624. (IF-5.83)

84. Jatin Sharma, Vijay Kumar Bhardwaj, Pralay Das, Rituraj Purohit*. Plant molecules identified as potential inhibitor against tobacco mosaic virus: A biosimulation approach, Pesticide Biochemistry and Physiology 2021, 104858. (IF-3.96)

81. Rahul Singh, Vijay Kumar Bhardwaj, Jatin Sharma, Pralay Das, Rituraj Purohit*. Identification of selective cyclin-dependent kinase 2 inhibitor from the library of pyrrolone-fused benzosuberene compounds: an in silico exploration, Journal of Biomolecular Structure and Dynamics 2021, doi.org/10.1080/07391102.2021.1900918. (IF-3.55)

80. Shankar Ram, Ajay Kumar Sharma, Arvind Singh Chauhan, Pralay Das*. Palladium-catalyzed ortho-halogen-induced deoxygenative approach of alkyl aryl ketones to 2-vinylbenzoic acids. Chem.Commun., 2020, 56, 10674-10677. Citation-3 (IF-6.22)

79. Dharminder Sharma, Manish Kumar, Pralay Das*.Application of Cyclohexane-1, 3-diones for Six-Membered Oxygen-Containing Heterocycles Synthesis, Bioorganic Chemistry, 2020, 107, 104559. Citation-4 (IF-5.27)

78. Ajay K. Sharma, Shankar Ram, Pushkar Mehara, Arvind Singh Chauhan, Pralay Das*. Supported Palladium‐Gold Catalyzed Carbonylative Methylthioesterification of Aryl Iodides using Oxalic acid and DMSO as CO and CH3SH Surrogates, Asian Journal of Organic Chemistry, 2020, 9 (12), 2099-2102.  (IF-3.3)

77. Rahul Singh, Vijay Bhardwaj, Pralay Das, Rituraj Purohit*. Natural analogues inhibiting selective cyclin-dependent kinase protein isoforms: a computational perspective, Journal of Biomolecular Structure and Dynamics, 2020, 38 (17), 5126-5135. Citation-25 (IF-3.55)

76. Shaifali, Sheetal, Rohit Bains, Ajay Kumar, Shankar Ram and Pralay Das*. Supported palladium catalyzed aminocarbonylation of aryl iodides employing bench-stable CO and NH3 surrogates. Org. Biomol. Chem., 2020, 18, 7193-7200. Citation-2 (IF-3.87)

75. Rahul Singh, Vijay K. Bhardwaj, Jatin Sharma, Pralay Das, Rituraj Purohit*. Discovery and in silico evaluation of aminoarylbenzosuberene molecules as novel checkpoint kinase 1 inhibitor determinants. Genomics, 2020, doi.org/10.1016/j.ygeno.2020.10.001. Citation-10 (IF-6.2)

74. Vijay K. Bhardwaj, Rahul Singh, Pralay Das, Rituraj Purohit*. Evaluation of acridinedione analogs as potential SARS-CoV-2 main protease inhibitors and their comparison with repurposed anti-viral drugs, Computers in Biology and Medicine, 2020, 128, 104117. Citation-8(IF-4.58)

73. Dhananjay Bhattacherjee*, Grigory V. Zyryanov, Pralay Das. Recent advances in the synthetic approaches to 2-pyridones. Chemistry of Heterocyclic Compounds, 2020, 56(9), 1152–1154. (IF-1.27)

72. Vijay Kumar Bhardwaj, Rahul Singh, Jatin Sharma, Pralay Das, Rituraj Purohit*. Structural based study to identify new potential inhibitors for Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase. Computer Methods and Programs in Biomedicine, 2020, 194, 105494. Citation-22(IF-5.42)

71. J Sharma, V Bhardwaj, Pralay Das, Rituraj Purohit*. Identification of naturally originated molecules as γ-aminobutyric acid receptor antagonist. Journal of Biomolecular Structure and Dynamics, 2020, 39 (3), 911-922. Citation-11(IF- 3.55)

70. Dhananjay Bhattacherjee, Shaifali Kang, Ajay Kumar, Ajay Sharma, Rituraj Purohit, Pralay Das*. Iodine (III) Promoted Ring-Rearrangement Reaction of 1-Arylamino-2-oxocyclopentane-1-carbonitriles to Synthesize N-Aryl-δ-valerolactams. Org. Biomol. Chem., 2020, 18, 745 –749. Citation-4 (IF-3.87)

69. R Singh, V Bhardwaj, Pralay Das, Rituraj Purohit*. Natural analogues inhibiting selective cyclin-dependent kinase protein isoforms: a computational perspective. Journal of Biomolecular Structure and Dynamics, 2019, 1-10. doi.10.1080/07391102.2019.1696709. (IF- 3.55)

68. Shankar Ram, Shaifali, Arvind Singh Chauhan, Sheetal, Ajay Kumar Sharma and Pralay Das*. Polystyrene supported palladium (Pd@PS) catalyzed carbonylative annulation of aryl iodides using oxalic acid as a sustainable CO source for the synthesis of 2‐aryl quinazolinones. Chem. Eur. J. 2019,25, 14506-14511. Citation-9(IF-5.23)

67. Shaifali, Shankar Ram, Vandna Thakur and Pralay Das*. Synthesis of α,β-alkynyl ketones via the nickel catalysed carbonylative Sonogashira reaction using oxalic acid as a sustainable C1 source. Org. Biomol. Chem., 2019, 17, 7036-7041. Citation- 9 (IF-3.87)

66. Dmitry S.Kopchuk, Nikolay V.Chepchugov, Ekaterina S.Starnovskaya, Albert F.Khasanov, Alexey P.Krinochkin, Sougata Santra, Grigory V. Zyryanov, Pralay Das, Adinath Majee, Vladimir L. Rusinov, Valery N. Charushin. Synthesis and optical properties of new 2-(5-arylpyridine-2-yl)-6-(het)arylquinoline-based “push-pull” fluorophores. Dyes and Pigments, 2019, 167, 151-156. Citation-7(IF-4.88)

65. Garima tanwar, Arindam Ghosh Mazumder, Vijay Bhardwaj, Savita Kumari, Richa Bharti, Yamini, Damanpreet Singh, Pralay Das, Rituraj Purohit*. Target identification, screening and in vivo evaluation of pyrrolone-fused benzosuberene compounds against human epilepsy using Zebrafish model of pentylenetetrazol-induced seizures. Scientific Reports, 2019, 9:7904. Citation- 17(IF-4.37)

64. C. Bal Reddy, Shankar Ram, Ajay Kumar, Richa Bharti, Pralay Das*. Supported palladium nanoparticles catalyzed aminocarbonylation of aryl halides with amines using oxalic acid as sustainable CO source. Chem. Eur. J. 2019, 25, 4067-4071. Citation-19 (IF-5.23)

63. Dhananjay Bhattacherjee, Shankar Ram, Arvind Singh Chauhan, Yamini, Sheetal, Pralay Das*, Hypervalent Iodine(III) Mediated Counter Anion Controlled Intramolecular Annulation of Exocyclic‐β‐Enaminone to Carbazolone and Imidazo[1,2‐a]pyridine Synthesis. Chem. Eur. J. 2019, 25, 5934-5939. Citation-11(IF-5.23)

62. Vandna Thakur, Ajay Sharma, Yamini, Nishtha Sharma, and Pralay Das*. Supported Palladium Nanoparticles-Catalyzed Synthesis of 3-Substituted 2-Quinolones from 2-Iodoanilines and Alkynes Using Oxalic Acid as C1 Source. Adv. Synth. Catal. 2019, 361, 426–431.Citation-12 (IF-5.85)

61. Saurabh Sharma, Ajay Sharma, Yamini, and Pralay Das*. Supported Rhodium (Rh@PS) Catalyzed Benzimidazoles Synthesis Using Ethanol/Methanol as C2H3/CH Source. Adv. Synth. Catal. 2019, 361, 67–72. Citation-11(IF-5.85)

60. Saurabh Sharma, Yamini and Pralay Das*. Hydrogenation of nitroarenes to anilines in a flow reactor using polystyrene supported rhodium in a catalyst-cartridge (Cart-Rh@ PS). New J. Chem., 2019, 43, 1764-1769. Citation-5(IF-3.28)

59. Saurabh Sharma, Dhananjay Bhattacherjee and Pralay Das*. Oxalic/malonic acids as carbon building blocks for benzazole, quinazoline and quinazolinone synthesis. Org. Biomol. Chem., 2018, 16, 1337-1342. Citation 16 (IF-3.56)

58. Saurabh Sharma, Dhananjay Bhattacherjee, and Pralay Das*. Supported Rhodium Nanoparticles Catalyzed Reduction of Nitroarenes, Arylcarbonyls and Aryl/Benzyl Sulfoxides using Ethanol/Methanol as in Situ Hydrogen Source. Adv. Synth. Catal. 2018, 360, 2131– 2137. Citation-10(IF-5.85)

57. Vandna Thakur, Ajay Kumar, Nishtha Sharma, Arun K. Shil and Pralay Das*. Supported Palladium Nanoparticles Catalyzed Reductive Carbonylation of Nitroarenes to N-Arylformamides. Adv. Synth. Catal. 2018, 360, 432–43. Citation-19 (IF-5.85)

56. Vandna Thakur, Sandeep Kumar and Pralay Das*.Polystyrene supported palladium nanoparticles catalyzed cinnamic acid synthesis using maleic anhydride as a substitute for acrylic acid. Catal. Sci. Technol., 2017,7, 3692-3697. Citation-9 (IF-5.72)

55. C. Bal Reddy, Richa Bharti, Sandeep Kumar, and Pralay Das*. Supported Palladium Nanoparticle Catalyzed α-Alkylation of Ketones Using Alcohols as Alkylating Agents. ACS Sustainable Chem. Eng., 2017, 5 (11), 9683–9691 Citation-19 (IF-7.63)

54. Richa Bharti, C. Bal Reddy, and Pralay Das*. Oxalic Acid as Sustainable CO Source for Pyrrolone-Fused Benzosuberenes Synthesis through Palladium Catalyzed Carbonylative Cyclization. ChemistrySelect, 2017, 2, 4626–4629. Citation 18 (IF-2.10)

53. Dhananjay Bhattacherjee, Vandna Thakur, Arun K.  Shil, Pralay Das*, Hypervalent iodine promoted aromatization of exo-cyclic β-enaminones for the synthesis of meta- N,N-diarylaminophenols. Adv. Synth. Catal. 2017, 359, 2202 –2208. Citation-16 (IF-5.85)

52. Dhananjay Bhattacherjee, Vandna Thakur, Saurabh Sharma, Sandeep Kumar, Richa Bharti, C. Bal Reddy, Pralay Das*, Iodine(III) Promoted Ring Contractive Cyanation of Exocyclic β-enaminones to Cyanocyclopentanone Synthesis.  Adv. Synth. Catal.  2017, 359, 2209–2214. Citation-16(IF-5.85)

51. Sandeep Kumar, Abha Chaudhary, Bandna, Dhananjay Bhattacherjee, Vandna Thakur and Pralay Das*. Supported Palladium Nanoparticles as Switchable Catalyst for Aldehyde Conjugate/s and Acetate Ester Synthesis from Alcohols. New Journal of Chemistry 2017, 41, 3242-3245. Citation-7 (IF-3.28)

50. Richa Bharti, C. Bal Reddy, Sandeep Kumar, Pralay Das*. Supported Palladium Nanoparticles Catalyzed Suzuki- Miyaura Cross-coupling Approach for Amino-Aryl-Benzosuberene Analogues Synthesis from Natural Precursor. Appl. Organometal Chem. 2017, 31(11), e3749. Citation-5 (IF-3.58)

49. Nitul Ranjan Guha, Vandna Thakur, Dhananjay Bhattacherje, Richa Bharti, Pralay Das*. Supported Rhodium Nanoparticle Catalyzed Intermolecular Regioselective Carbonylative Cyclization of Terminal Alkynes Using Oxalic Acid as Sustainable C1 Source.  Adv. Synth. Catal. 2016, 358, 3743-3747. Citation-15(IF-5.85)

48. Sandeep Kumar, Saurabh Sharma and Pralay Das*. Supported Gold Nanoparticles-Catalyzed Microwave-Assisted Hydration of Nitriles to Amides under Base-Free Conditions. Adv. Synth. Catal. 2016, 358, 2889-2894. Citation-16 (IF-5.85)

47. C. Bal Reddy, Richa Bharti, Sandeep Kumar, and Pralay Das*. Supported palladium nanoparticles-catalyzed decarboxylative coupling approaches to aryl alkynes, indoles and pyrrolines synthesis. RSC Adv., 2016, 6, 71117-71121. Citation-18 (IF-3.36)

46. Nitul Ranjan Guha, Saurabh Sharma, Dhananjay Bhattacherje, Vandna Thakur, Richa Bharti, C. Bal Reddy, Pralay Das*. Oxidative “reverse-esterification” of ethanol with benzyl/alkyl alcohols or aldehydes catalyzed by supported rhodium nanoparticles. Green Chemistry, 2016, 18, 1206-1211. Citation-21(IF-9.48)

45. Vandna Thakur, Dharminder Sharma, Pralay Das*. Ethyl 3-(2,4-dioxocyclohexyl) propanoate as a novel precursor for N-substituted 4,4a,5,6-tetrahydroquinoline-2,7(1H,3H)-diones and their corresponding 3,4-dihydro-7-hydroxyquinolin-2(1H)-ones and 7-hydroxyquinolin-2(1H)-ones synthesis. Mol Divers 2016, 20, 29–40. Citation- 3 (IF-2.22)

44. Arun K. Shil, Sandeep Kumar, C. Bal Reddy, Sumit Dadhwal, Vandna Thakur and Pralay Das*. Supported Palladium Nanoparticle-Catalyzed Carboxylation of Aryl Halides, Alkenylsilanes, and Organoboronic Acids Employing Oxalic Acid as the C1 Source. Org. Lett., 2015, 17 (21), pp 5352–5355. Citation-46(IF-6.09)

43. Nitul Ranjan Guha, Dhananjay Bhattacherjee and Pralay Das*. Polystyrene trimethyl ammonium chloride impregnated Rh(0) (Rh@PMe3NCl) as a catalyst and methylating agent for esterification of alcohols through selective oxidation of methanol. Catal. Sci. Technol., 2015, 5, 2575–2580.  Citation-8 (IF-5.72)

42. Arun K. Shil and Pralay Das*. Polystyrene resin supported palladium(0) (Pd@PR) nanocomposite catalyzed synthesis of β-aryl and β,β-diaryl unsaturated scaffolds following tandem approaches. RSC Adv., 2015, 5, 24859-24863. Citation-9(IF-3.36)

41. Arun K Shil, Sandeep Kumar, Saurabh Sharma, Abha Chaudhary and Pralay Das*.  Polystyrene resin supported palladium(0) (Pd@PR) nanocomposite mediated regioselective synthesis of 4-aryl-1-alkyl/(2-haloalkyl)-1H-1,2,3-triazoles and their N-vinyl triazole derivatives from terminal alkynes. RSC Adv., 2015, 5, 11506-11514. Citation-11(IF-3.36)

40. Abha Chaudhary and Pralay Das*. Strategies for Functionalized Benzocycloheptene amines Synthesis. Current Organic Chemistry, 2015, 19(2), 179-196. Citation-4 (IF-2.02)

39. Nitul Ranjan Guha, Dhananjay Bhattacherjee, Pralay Das*. Solid supported rhodium(0) nanoparticles: An efficient catalyst for chemo- and regio-selective transfer hydrogenation of nitroarenes to anilines under microwave irradiation. Tetrahedron Lett. 2014, 55, 2912-2916. Citation-31(IF-2.37)

38. C. Bal Reddy, Arun K. Shil, Nitul Ranjan Guha, Dharminder Sharma, and Pralay Das*. Solid Supported Palladium(0) Nanoparticles: An Efficient Heterogeneous Catalyst for Regioselective Hydrosilylation of Alkynes and Suzuki Coupling of β-Arylvinyl Iodides. Catalysis lett., 2014, 144, 1530-1536. Citation-20 (IF-2.79)

37. Abha Chaudhary, Swati Sood, Pralay Das, Pushpinder Kaur, Isha Mahajan, Arvind Gulati, Bikram Singh*. Synthesis of Novel Antimicrobial Aryl Himachalene Derivatives from Naturally Occurring Himachalenes. EXCLI Journal 2014, 13, 1216-1225. Citation-7(IF-2.83)

36. Arun K Shil and   Pralay Das*. Solid Supported Platinum(0) Nanoparticles Catalyzed Chemo-selective Reduction of Nitroarenes to N-Arylhydroxylamines. Green Chemistry, 2013, 15, 3421–3428. Citation-55 (IF. 9.48)

35. Sandeep Kumar and Pralay Das*. Solid-supported ruthenium(0): an efficient heterogeneous catalyst for hydration of nitriles to amides under microwave irradiation. New J. Chem., 2013, 37, 2987-2990. Citation-35(IF. 3.28)

34. Arun K. Shil, Nitul Ranjan Guha, Dharminder Sharma, Pralay Das*. Solid supported palladium (0) nano/microparcles catalyzed ultrasound induced continuous flow technique for large scale Suzuki reaction. RSC Advances., 2013, 3, 13671-13676. Citation-26 (IF. 3.36)

33. Dharminder Sharma, C. Bal Reddy, Arun K. Shil, Rashi Prakash Saroach, Pralay Das*. Cyclohexyl iodide promoted approach for coumarin analogue synthesis using small scaffold. Molecular Diversity, 2013, 17, 651–659. Citation-14(IF-2.22)

32. Pralay Das*, Nidhi Aggarwal, Nitul Ranjan Guha. Solid supported Ru(0) nanoparticles: an efficient ligand-free heterogeneous catalyst for aerobic oxidation of benzylic and allylic alcohol to carbonyl. Tetrahedron Lett. 2013, 54, 2924-2028. Citation-34(IF-2.37)

31. Dharminder Sharma, Bandna, C. Bal Reddy, Sandeep Kumar, Arun K. Shil, Nitul Ranjan Guha and Pralay Das*. Microwave assisted solvent and catalyst free method for novel classes of β-enaminoester and acridinedione synthesis. RSC Advances, 2013, 3, 10335-10340. Citation-11 (IF- 3.36)

30. Bandna, Dharminder Sharma, and Pralay Das*. Cyanoalkyl amines: as an efficient reagent to stabilize palladium nano/microparticles for Suzuki and basic media for palladium(II) catalyzed Heck cross coupling reaction. Nano Bulletin 2013, 2(2), 130211 (Invited).

29. Vikas Jaitak, V. K. Kaul* and Pralay Das. Enviornmentally benign Michael and Claisen Schmidt reaction of aromatic carbonyl compounds by alkaline polyionic resin. Indian J. Chem., 2013, 52B (8), 1137-1145. (IF-0.38)

28. Nitul Ranjan Guha, Chennayala Bal Reddy, Nidhi Aggarwal, Dharminder Sharma, Arun K Shil, Bandna, Pralay Das*. Solid supported Rh(0) nano/microparticles: an efficient ligand free heterogeneous catalyst for microwave assisted Suzuki-Miyaura cross coupling reaction. Adv. Synth. Catal. 2012, 354, 2911-2915. Citation-37 (IF-5.85)

27. Dharminder Sharma, Sandeep Kumar, Arun K. Shil, Nitul Ranjan Guha, Bandna, Palay Das*. Solid supported palladium(0) nano/microparticle: a ligand-free efficient recyclable heterogeneous catalyst for mono- and β,β-double-Heck reaction. Tetrahedron lett. 2012, 53, 7044-7051. Citation-22 (IF-2.37)

26. Arun K. Shil, Dharminder Sharma, Nitul Ranjan Guha and Pralay Das*. Solid supported Pd(0): an efficient recyclable heterogeneous catalyst for chemoselective reduction of nitroarenes. Tetrahedron Lett. 2012, 53, 4858-4861. Citation-120 (IF-2.37)

25. Bandna, Nitul Ranjan Guha, Arun K. Shil, Dharminder Sharma, Pralay Das*. Ligand free solid supported Palladium(0) nano/microparticles promoted C-O, C-S and C-N cross-coupling reaction. Tetrahedron Lett. 2012, 53, 5318–5322. Citation-47 (IF-2.37)

24. Abha Chaudhary, Pralay Das, Awanish Mishra, Pushpinder Kaur, Bikram Singh*, Rajesh K. Goel. Naturally occurring himachalenes to benzocycloheptene amino vinyl bromide derivatives: as antidepressant molecules. Molecular Diversity, 2012, 16 (2), 357-366. Citation-18(IF-2.22)

23. Pushpinder Kaur, Pralay Das, Abha Chaudhary and Bikram Singh*. Naturally occurring limonene to cinnamyl-type γ-butyrolactone substituted aldol condensation derivatives as antioxidant compounds. Natural Product Communications, 2012, 7 (9), 1127-1130. Citation-3(IF-0.55)

22. Dharminder Sharma, Bandna, Arun K. Shil, Bikram Singh, Pralay Das*. Consecutive Michael-Claisen process for cyclohexane-1,3-dione derivatives (CDD) synthesis from unsubstituted and substituted acetone. Synlett, 2012, 23(8) 1199-1204. Citation-14 (IF-2.36)

21. Bandnaa, Nidhi Aggarwala, Pralay Das*. Solid-supported Pd(0): an efficient heterogeneous catalyst for aerobic oxidation of benzyl alcohols into aldehydes and ketones. Tetrahedron Lett. 2011, 52, 4954-4956. Citation-36(IF-2.37)

20. Pralay Das*, Dharminder Sharma, Arun K. Shil, Avnesh Kumari. Solid-supported palladium nano and microparticles: an efficient heterogeneous catalyst for ligand-free Suzuki–Miyaura cross coupling reaction. Tetrahedron Lett. 2011, 52, 1176-1178. Citation-70 (IF-2.37)

19. Erik Chorell, Christoffer Bengtsson, Thomas Sainte-Luce Banchelin, Pralay Das, Hanna Uvell, Arun K. Sinha, Jerome S. Pinkner, Scott J. Hultgren and Fredrik Almqvist*. Synthesis and application of a bromomethyl substituted scaffold to be used for efficient optimization of antivirulence activity. European Journal of Medicinal Chemistry, 2011, 46, 1103-1116. Citation-27 (IF-5.57)

18. Pushpinder Kaur, Pralay Das, Abha Chaudhary, Bikram Singh*. Amine and thiazole substituted γ-butyrolactones from naturally occurring limonene. Canadian Journal of Chemistry, 2011, 89, 1-6. Citation-2 (IF-1.17)

17. Indra Sandal, Amita Bhattachary*, Uksha Saini, Devinder Kaur, Shveta Sharma, Ashu Gulati, Jonnala  K Kumar, Neeraj Kumar, Jyotsna Dayma, Pralay Das, Bikram Singh, Paramvir S Ahuja. Chemical modification of L-glutamine to alpha-amino glutarimide on autoclaving facilitates Agrobacterium infection of host and non-host plants: a new use of a known compound. BMC Chemical Biology, 2011, 11:1. Citation-9 (IF-2.0)

16. Vikash Jaitak, Bandna, Pralay Das, V. K. Kaul, Neeraj Kumar and Bikram Singh. One-pot multicomponent Michael and Thorpe-Ziegler reaction of aryl methyl ketones. Synth. Commun. 2011, 41, 2727-2737. (IF-1.79)

15. Pralay Das*, Dharminder Sharma, Manish Kumar, Bikram Singh. Copper promoted C-N and C-O type cross-coupling reactions. Current Organic Chemistry, 2010, 14(8), 754-783. Citation-39 (IF-1.93)

14. Basudeb Basu*, Sajal Das, Pralay Das, Bablee Mandal, D. Banerjee and Fredrik Almqvist. Palladium supported on poly-ionic resins as efficient, ligand free and recyclable catalyst for Heck, Suzuki-Miyaura and Sonagashira reactions. Synthesis, 2009, 1137-1146. Citation-42 (IF-2.67)

13. Basudeb Basu*, Bablee Mandal, Sajal Das, Pralay Das and Ashis K. Nanda. Chemoselective reduction of aldehydes by ruthenium trichloride and resin-bound formats. Beilstein J. Org. Chem. 2008, 4, 53. Citation-19 (IF-2.62)

12. Basudeb Basu*, Pralay Das and Sajal Das. Recent Advances in KF/alumina Promoted Organic Reactions. Current Organic Chemistry, 2008, 12(2), 141-158. Citation-42 (IF-1.93)

11. V. Åberg, Pralay Das, Erik Chorell, M. Hedenström, Jerome S. Pinkner, S. J. Hultgren, Fredrik Almqvist*. Carboxylic acid isosteres improve the activity of ring-fused 2-pyridones that inhibit pilus biogenesis in E. coli. Bioorg. Med. Chem. Lett. 2008, 18, 3536-3540. Citation-42(IF-2.57)

10. Erik Chorell, Pralay Das and Fredrik Almqvist*. Diverse functionalization of thiazolo ring-fused 2-pyridones. J. Org. Chem. 2007, 72, 4917-4924. Citation-31(IF-4.80)

9. Basudeb Basu*, Pralay Das, Sajal Das. Transfer hydrogenation using recyclable polymer-supported formate (PSF): Efficient and chemoselective reduction of nitroarenes. Molecular Diversity, 2005, 9(4), 259. Citation-20(IF-2.22)

8. Basudeb Basu*, Sajal Das, Pralay Das, Ashis K. Nanda. Co-immobilized formate anion and palladium on a polymer surface: a novel heterogeneous combination for transfer hydrogenation. Tetrahedron Lett. 2005, 46, 8591-8593. Citation-29 (IF-2.37)

7. Basudeb Basu*, Pralay Das, Ashis K. Nanda, Sajal Das, Sajal Sarkar. Palladium-catalyzed selective amination of haloaromatics on KF-alumina surface. Synlett. 2005, 16 (8), 1275-1278. Citation-14 (IF-2.36)

6. Basudeb Basu*, Pralay Das, Ismail Hossain. Synthesis of β-amino esters via aza-Michael addition of amines to alkenes promoted on silica: a useful and recyclable surface. Synlett. 2004, 15 (14), 2630-2632. Citation-40 (IF-2.36)

5. Basudeb Basu*, Pralay Das, Ismail Hossain. KF-alumina-mediated selective double Michael additions of aryl methyl ketones: a facile entry to the synthesis of functionalized pimelate esters and derivatives. Synlett. 2004, 15 (12), 2224-2226. Citation-14(IF-2.36)

4. Pralay Das and Basudeb Basu*. Microwave-assisted copper promoted N-arylation of amines with aryl boronic acids/salts on a KF–alumina surface. Synth. Commun. 2004, 34(12), 2177 – 2184. Citation-23(IF-1.79)

3. Basudeb Basu*, Pralay Das, Md. M. H. Bhuiyan and Satadru Jha. Microwave-assisted Suzuki coupling on a KF–alumina surface: synthesis of polyaryls. Tetrahedron Lett. 2003, 44(19), 3817-3820. Citation-107 (IF-2.37)

2. Basudeb Basu*, Md. M. H. Bhuiyan, Pralay Das, Ismail Hossain. Catalytic transfer reduction of conjugated alkenes and an imine using polymer-supported formats. Tetrahedron Lett. 2003, 44 (50), 8931-8934. Citation-70 (IF-2.37)

1. Basudeb Basu*, Satadru Jha, Md. M. H. Bhuiyan, Pralay Das. A simple protocol for direct reductive amination of aldehydes and ketones using potassium formate and catalytic palladium acetate. Synlett. 2003, 14 (4), 555-557. Citation-30(IF-2.36)

Patents

7. Pralay Das, Arvind S. Chauhan, Ajay Kumar. Metal Free Approaches for Selective Reduction of Aldehyde to Methyl Group of Different Substituted Furans. IN2020110070682019, 2020.

6. Pralay Das, Yamini, Richa Bharti, Shankar Ram, Vijay K. Bhardwaj, Rituraj Purohit, Damanpreet Singh, Prince Anand, Yogendra S Padwad. Bioactive benzocycloheptene analogues from himachalenes and its applications. 202011045582, 2020.

5. Pralay Das, Ajay Kumar, Shaifali. Process development for 5-hydroxymethylfurfural (5-HMF) synthesis from carbohydrates. 20210122722, WO2019244166, PCT/IN2019/050116, IN201811023331, CN112543754, US20210122722, EP3810583, RU2020142264.

4. Pralay Das, Dharminder Sharma, Bikram Singh. Substituted cyclohexane-1,3-dione compounds, process for preparation thereof and its applications. WO/2011/117881, 2011, US8916723B2, PCT/IN2011/000180.

3. Fredrik Almqvist, M. Sellstedt, Pralay Das. New Peptidomimetic Compounds. WO/2009/134203, 2009, PCT/SE2009/050464, CA2633397, EP2100720, EP2276769, US20110160241, CN102066385, AU2009243232, JP2011519372, CA2722938 IN7665/DELNP/2010.

2. Fredrik Almqvist, Erik Chorell, Pralay Das, H. Emtenas, O. Fjellstrom, M. Mogemark, M. Polla, V. Aberg. 1H-Pydidine-2-one derivatives useful in treatment of PAI-1 related disorders. WO/2008/054290, 2008.

1. Fredrik Almqvist, Erik Chorell, Pralay Das, Hans Emtenas, Ola Fjellstrom, Mickael Mogemark, Magnus Polla, Veronica Aberg. New compounds. 20080139607.

Research Group

Ph.D. Awarded:

  1. Dr. Dharminder Sharma: GNDU-2013;
  2. Dr. Bandna: GIDU-2013;
  3. Dr. Arun Kumar Shil: AcSIR-2015;
  4. Dr. Nitul Ranjan Guha: AcSIR-2016
  5. Dr. Sandeep Kumar: AcSIR-2017
  6. Dr. Richa Bharti: AcSIR-2017
  7. Dr. C. Bal Reddy: AcSIR-2017
  8. Dr. Vandna Thakur: AcSIR-2018
  9. Dr. Saurabh Sharma: AcSIR-2018
  10. Dr. Dhananjay Bhattacherjee: AcSIR-2019

 

Present Research Group:

Ph.D. Fellow:

  1. Shaifali, SRF-UGC
  2. Shankar Ram, SRF-CSIR
  3. Ajay Kumar Sharma, DST-INSPIRE Fellow
  4. Arvind Singh Chauhan, DST-INSPIRE Fellow
  5. Sheetal- CSIR-UGC
  6. Ashish Kumar, CSIR-JRF
  7. Ajay Kumar, JRF
  8. Yamini, CSIR, PA-II
  9. Pushkar Mehara, CSIR-JRF
  10. Rohit Bains, CSIR-JRF
  11. Poonam Sharma, CSIR-JRF

Former members:

  1. Dharminder Sharma, Assistant Professor, Arni University, Kangra, H.P.
  2. Abha Chaudhary: Assistant Professor, Kurukshetra University, Haryana
  3. Manish Kumar: Assistant Professor, DAV University, Jalandhar
  4. Sumit Dadhwal: Ph.D. fellow, University of Otago, New Zealand
  5. Nidhi Agarwal: RI up to February 2012